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| Rakesh Sharma; Suniket Fulzele; Kiran Shetty; Mandeep Sachdeva; Bruce R. Locke. |
| *Aim:* A rapid ultra high resolution ex vivo MRI imaging method was evaluated to visualize rat skin structure. The main objectives were:1.qualitative assessment of viable epidermis, hair, oil and fat-rich skin features by multi-contrast approach;2.achievement of spatial resolution up to 15 microns; 3.comparison of skin histology with MRI skin features obtained by 21 Tesla magnetic resonance imaging (MRI) imager. 

*Introduction:* The ultrawide bore 900 MHz magnet has high resolution NMR magnet has a central field of 21.1 T. The high resolution MRI technique has potential for both quantitative and non-invasive morphological evaluation at micrometer level. The MRI signal was sensitive to water protons and glycolipid... |
| Tipo: Poster |
Palavras-chave: Biotechnology. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/2639/version/1 |
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| Rakesh Sharma. |
| Superparamagnetic iron-oxide bound antimyoglobin (SPIOM) characteristics were analyzed at different pH. After injecting SPIOM in heart, ex vivo magnetic resonance microimaging (MRM) technique was used to visualize microvasculature of rat heart including cardiac arteries, veins, cordate tendons attached with valves. The measurement accuracy of ventricles, aorta, vasculature and dimensions of cordate tendons were close to coregistered histology measurements. |
| Tipo: Poster |
Palavras-chave: Biotechnology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/2643/version/2 |
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| Rakesh Sharma. |
| Superparamagnetic iron-oxide bound antimyoglobin (SPIOM) characteristics were analyzed at different pH. After injecting SPIOM in heart, ex vivo magnetic resonance microimaging (MRM) technique was used to visualize microvasculature of rat heart including cardiac arteries, veins, cordate tendons attached with valves. The measurement accuracy of ventricles, aorta, vasculature and dimensions of cordate tendons were close to coregistered histology measurements. |
| Tipo: Poster |
Palavras-chave: Biotechnology. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/2643/version/1 |
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| S Sharma; Rakesh Sharma. |
| Excised mice kidney, heart and skin MRI visible features were quantitated using ex vivo 21 Tesla MRI microimager. The fast MRI acquisition protocols of FLASH, gradient echo flow compensated (GEFC) techniques were used to visualize microvasculature of mice kidney, mice heart including cardiac arteries, veins, cordate tendons and mice skin epidermis with hair follicle features. |
| Tipo: Presentation |
Palavras-chave: Biotechnology. |
| Ano: 2009 |
URL: http://precedings.nature.com/documents/3484/version/1 |
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| Xuri Wu; Nan Liu; Yunmian He; Yijun Chen. |
| Various ketoreductases exclusively participate in all common biological events, and they are a class of important biocatalysts for the production of chiral alcohols. While many types of ketoreductase have been extensively studied and their functions, properties and utilities have been well known, the capability of stereoselectively reducing two carbonyl groups in the same diketohexanoate ester molecule to form a dihydroxy product by a single ketoreductase has not been evidently characterized. Here we show that a unique and novel enzyme, diketoreductase, was cloned from Acinetobacter baylyi, heterogeneously expressed in _Escherichia coli_ and purified to homogeneity. The diketoreductase is up to 78% homologous to bacterial 3-hydroxyacyl coenzyme-A... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology; Chemistry; Microbiology. |
| Ano: 2008 |
URL: http://precedings.nature.com/documents/1697/version/1 |
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| Xuri Wu; Nan Liu; Yunmian He; Yijun Chen. |
| Various ketoreductases exclusively participate in all common biological events, and they are a class of important biocatalysts for the production of chiral alcohols. While many types of ketoreductase have been extensively studied and their functions, properties and utilities have been well known, the capability of stereoselectively reducing two carbonyl groups in the same diketohexanoate ester molecule to form a dihydroxy product by a single ketoreductase has not been evidently characterized. Here we show that a unique and novel enzyme, diketoreductase, was cloned from Acinetobacter baylyi, heterogeneously expressed in _Escherichia coli_ and purified to homogeneity. The diketoreductase is up to 78% homologous to bacterial 3-hydroxyacyl coenzyme-A... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology; Chemistry; Microbiology. |
| Ano: 2010 |
URL: http://precedings.nature.com/documents/1697/version/2 |
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| Rumin, Judith; Nicolau, Elodie; Gonçalves De Oliveira Junior, Raimundo; Fuentes-grünewald, Claudio; Flynn, Kevin J; Picot, Laurent. |
| A bibliographic database of scientific papers published by authors affiliated worldwide, especially focused in Europe and in the European Atlantic Area, and containing the keywords “microalga(e)” or “phytoplankton” was built. A corpus of 79,020 publications was obtained and analyzed using the Orbit Intellixir software to highlight the evolution of the research domain. Publication rates from 1960 to 2019, organization of the research, collaboration networks between countries and organizations, emerging and fading research concepts, major studied species, and associated concepts, as well as journals publishing microalgae research were considered. As a result, of the 79,020 papers published worldwide, 26,137 included authors from Europe (33% of world... |
| Tipo: Text |
Palavras-chave: Biotechnology; European Atlantic Area; Microalgae; Phytoplankton; Research; Market; Bibliometrics. |
| Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00605/71725/70191.pdf |
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| Donald C. Cooper. |
| “A disruptive innovation is an innovation that helps create a new market and value network, and eventually goes on to disrupt an existing market and value network (over a few years or decades), displacing an earlier technology. The term is used in business and technology literature to describe innovations that improve a product or service in ways that the market does not expect.” -Wikipedia
On April 3rd, 2012 Nature Precedings, Nature Publishing Group’s experiment in free pre-print publishing was shut down and no longer accepts submissions. According to the Nature Precedings website it was created in 2007 as “a place for researchers to share documents, including presentations, posters, white... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology; Neuroscience; Bioinformatics. |
| Ano: 2012 |
URL: http://precedings.nature.com/documents/7151/version/1 |
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| Shaheed SM; Rohit JP; Madhan R; Selvakumar K. |
| Ethanol derived from non-edible biomass is renewable and a clean source of energy. It is independent of the food industry and it is economically feasible. The first generation biofuel or bioethanol is still not a very convenient source of energy as it prominently depends on the availability of grains. The main objective of this work is to develop an industrious efficient process to produce ethanol from lignocellulosic biomasses like wood and leaf in a lab scale. Two processes were compared. The first process involved an alkaline pre-treatment of the powdered biomass followed by dilute acid hydrolysis. The second process involved an alkaline treatment followed by direct hydrolysis of the biomass by use of a fungal species obtained from rotting wood.... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology. |
| Ano: 2011 |
URL: http://precedings.nature.com/documents/6579/version/1 |
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| Petra Zürbig; Joshua Coon; Hartwig Bauer; Georg Behrens; Mohammed Dakna; Anna Dominiczak; Stephane Decramer; Jochen Ehrich; Danilo Fliser; Moritz Frommberger; Arnold Ganser; Mark Giolami; Igor Golovko; David Good; Wilfried Gwinner; Marion Haubitz; Stefan Herget-Rosenthal; Holger Jahn; George Jerums; Bruce Julian; Markus Kellmann; Volker Kliem; Walter Kolch; Andrzej Krolewski; Mario Luppi; Ziad Massy; Michael Melter; Christian Neusüss; Jan Novak; Karlheinz Peter; Kasper Rossing; Harald Rupprecht; Joost Schanstra; Eric Schiffer; Jens-Uwe Stolzenburg; Lise Tarnow; Dan Theodorescu; Visith Thongboonkerd; Raymond Vanholder; Eva Weissinger; Harald Mischak; Philippe Schmitt-Kopplin. |
| Owing to its availability, ease of collection and correlation with (patho-) physiology, urine is an attractive source for clinical proteomics. However, the lack of comparable datasets from large cohorts has greatly hindered development in this field. Here we report the establishment of a high resolution proteome database of naturally occurring human urinary peptides and proteins - ranging from 800-17,000 Da - from over 3,600 individual samples using capillary electrophoresis coupled to mass spectrometry, yielding an average of 1,500 peptides per sample. All processed data were deposited in an SQL database, currently containing 5,010 relevant unique urinary peptides that serve as classifiers for diagnosis and monitoring of diseases, including kidney and... |
| Tipo: Manuscript |
Palavras-chave: Biotechnology. |
| Ano: 2007 |
URL: http://precedings.nature.com/documents/1219/version/1 |
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| Linacre, Nicholas A.; Cohen, Joel I.. |
| The regulatory approval of genetically modified crops in the field initially requires small, restricted experimental trials known as confined field trials. These small scale experiments provide researchers with important information on environmental interactions and agronomic performance of the crop in a safe and contained manner. To authorize confined field trials regulatory review is required, with formats for obtaining relevant information differing from country to country. In this paper, a Gap Analysis is used to identify informational gaps and potential for harmonization of confined field trial application processes in three East African countries - Tanzania, Kenya, and Uganda. The basic principle behind gap analysis is a comparison of the status quo... |
| Tipo: Report |
Palavras-chave: Genetically modified crops; Gap analysis; Confined field trials; Biotechnology; Biosafety; Crop Production/Industries. |
| Ano: 2006 |
URL: http://purl.umn.edu/55421 |
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| Lusk, Jayson L.; Jamal, Mustafa; Kurlander, Lauren; Roucan, Maud; Taulman, Lesley. |
| A plethora of research in recent years has been devoted to estimating consumer demand for genetically modified food, an important piece of information needed to create appropriate public policy. To examine this body of work, a meta-analysis was conducted of 25 studies that, in aggregate, report 57 valuations for GM food. Findings indicate as much as 89% of the variation in existing value estimates for genetically modified food can be explained by an econometric model that controls for (a) the characteristics of the sample of consumers studied, (b) the method for eliciting consumers' valuation, and (c) characteristics of the food being valued. Each of these factors has a statistically significant effect on estimated premiums for non-GM food. Results of... |
| Tipo: Journal Article |
Palavras-chave: Biotechnology; Consumer acceptance; Genetically modified food; Willingness to pay; Consumer/Household Economics. |
| Ano: 2005 |
URL: http://purl.umn.edu/30782 |
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